Projects underway
Drugs
| Classification | Seeds Title | Affiliation | Name |
|---|---|---|---|
| Cancer | Development of magnetic nanoparticles for theranostics | Yokohama National University | Yuko ICHIYANAGI |
| Cancer | Development of anti-cancer drug with immunomodulators | Initiative for Advanced Research, Gunma University | Keisuke NIMURA |
| Cancer | Research aiming to develop refractory cancer therapeutics using protein-based drug delivery systems with drug release control function | Graduate School of Agriculture, Osaka Metropolitan University | Takashi INUI |
| Cancer | Development of innovative antibody therapy against ovarian cancer by controlling lipid metabolism (Acquisition of non-clinical POC for novel antibody therapy using anti-LSR antibody for ovarian cancer) | Institute for Biomedical Sciences, Division of Drug Discovery and Medical | Tetsuji NAKA |
| Cancer | Targeted alpha-ray therapy for refractory thyroid cancer | Institute for Radiation Sciences, The University of Osaka | Tadashi WATABE |
| Cancer | Development of a new treatment for chemotherapy-resistant triple-negative breast cancer | Department of Advanced Molecular Therapy,Graduate School of Medicine, The University of Osaka | Yoshiaki TANIYAMA |
| Cancer | Innovative alpha therapy targeting PSMA for refractory prostate cancer | Institute for Radiation Sciences, The University of Osaka | Tadashi WATABE |
| Brain and Psychiatry | Development of ASOs for multiple system atrophy | 1. Department of Neurology, Graduate school of Medicine, The University of Osaka 2. Osaka Toneyama Medical Center |
Yasuyoshi KIMURA1、 Hideki MOCHIZUKI2 |
| Brain and Psychiatry | Sensory medicine: Innovative therapeutics based on the principle of inducing the artificial hibernation / life-protective state by TRPA1 - activating odor molecules | Kansai Medical University | Ko KOBAYAKAWA |
| Brain and Psychiatry | Development of a novel therapeutic drug for schizophrenia | Graduate School of Biomedical and Health Sciences, Hiroshima University | Yukio AGO |
| Infectious diseases | Development of therapeutic strategy for mosquito-borne diseases by targeting mosquito saliva | Department of Microbiology, Graduate School of Medicine,Juntendo University | Tatsuya SUZUKI |
| Infectious diseases | Development of a novel antibacterial that targets a molecular chaperone | Faculty of Engineering, Tottori University | Tomohiro MIZOBATA |
| Infectious diseases | Development of SE36-cVLP Malaria Vaccine | Laboratory of Malaria Vaccine Development,Research Institute for Microbial Diseases,The University of Osaka | Toshihiro HORII |
| Cardiovascular diseases | Development of L862, an Innovative Pulmonary Hypertension Treatment Targeting TRPC3/6 | 1. The University of Osaka, Pharmaceutical Sciences 2. Shinshu University School of Medicine |
Ryu NAGATA1、 Koichiro KUWAHARA2 |
| Cardiovascular diseases | Development of novel companion PET diagnostics and therapeutic agents for myocarditis | Department of Medical Biochemistry,Graduate School of Medicine, The University of Osaka | Ken MATSUOKA |
| Intractable diseases | Development of Therapeutic Agents for Intractable Neurological Diseases Using Novel GAPDH Aggregation Inhibitors | Osaka Metropolitan University | Hidemitsu NAKAJIMA |
| Others | Development of single-molecule imaging-based screening technology for drug discovery | Graduate School of Frontier Biosciences, The University of Osaka | Masahiro UEDA |
| Others | Discovering Peptide-based Therapeutics for Neuropathic Pain | Department of Biomedical Engineering, Osaka Institute of Technology | Emiko OKUDA-ASHITAKA |
| Others | Tissue targeting of lipid nanoparticles by N-terminal modification of peptides | Faculty of Environmental Earth Science, Hokkaido University | Akira ONODA |
| Others | Development of repair therapy for skin barrier function by product lipids of novel lipase | Department of Bio-system Pharmacology,Graduate School of medicine, The University of Osaka | Ryuichi OHGAKI |
| Others | Establishment of a new strategy for the treatment of functional restoration in skeletal muscle injury by tissue engineering using osteopontinederived SVVYGLR peptide | Department of Oral and Maxillofacial Surgery,Graduate School of Dentistry, The University of Osaka | Susumu TANAKA |
| Others | A new anti-inflammatory drug that utilizes the active site of an endogenous NFkB direct inhibitory protein | Graduate School of Frontier Biosciences, The University of Osaka | Kazuki OKAMOTO |
Medical devices
| Seeds Title | Affiliation | Name | |
| Development of a new disinfection device using Pernitric acid solution | Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, The University of Osaka | Katsuhisa KITANO | |
| Novel diagnostic marker to differentiate urogenital carcinoma by chiral amino acids in body fluids | Department of Urology, Graduate School of Medicine, The University of Osaka | Atsunari KAWASHIMA | |
| Development of a robot arm for bone processing | Department of Orthopaedic Surgery, Graduate School of Medicine, The University of Osaka | Takahito FUJIMORI | |
| Raman spectroscopic tissue detection for minimally-invasive and precise medicine | Institute for Open and Transdisciplinary Research Initiatives, The University of Osaka | Yasuaki KUMAMOTO | |
| Development of highly efficient automatic bone marrow stem cell separate system for treatment of stroke patients | Department of Regenerative Medicine Research, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe | Akihiko TAGUCHI | |
| Development of “peptide” pulp capping agent promoting wound healing process of pulp tissue | The University of Osaka Dental Hospital | Yusuke TAKAHASHI | |
| Development of a valved extracardiac conduit using in situ tissue restoration | Department of Thoracic and Cardiovascular Surgery, Osaka Medical and Pharmaceutical University | Shintaro NEMOTO | |
| Tumor diagnosis technology using AI analysis of the light spectrum of cytological specimens | Medilux Research Center, Nara Institute of Science and Technology (NAIST) | Yoichiroh HOSOKAWA | |
| Restoration of Motor and Communication by Wireless Implantable Brain Machine Interfaces | Department of Neurological Diagnosis and Restoration, Graduate School of Medicine, The University of Osaka | Masayuki HIRATA | |
Regenerative medicine
| Seeds Title | Affiliation | Name | |
|---|---|---|---|
| Human Gastric Tissue Epithelial Stem Cell Organoid Expansion Culture Technology | Graduate School of Science and Technology, Nara Institute of Science and Technology (NAIST) | Akira KURISAKI、 Hitomi TAKADA |
|
| Development of a Novel Culture Container Enabling Simplified Mass Production of Cells | Applied Chemistry Course, Department of Materials Science, Akita University | Ikki HORIGUCHI | |
| Repair of incurable meniscal injuries using an aligned electrospun nanofibrous scaffold | Department of Orthopaedic Surgery,Graduate School of Medicine, The University of Osaka | Kazunori SHIMOMURA | |
| Study aiming to produce human iPSC-derived cell formulation for metabolic hepatic disorder | Department of iPS Stem Cell Regenerative Medicine, Kansai Medical University | Yasumasa SHIROUZU | |
| Development of oncolytic adenovirus agents composed of human adenovirus type 35 | Graduate School of Pharmaceutical Sciences, The University of Osaka | Hiroyuki MIZUGUCHI | |
| Development of gene therapy for arrhythmogenic right ventricular cardiomyopathy | Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Osaka | Shuichiro HIGO | |
| Development of Liver Assist Device Using Hypoimmunogenic Hepatocyte System | Graduate School of Medicine, The University of Osaka | Takanori TAKEBE | |
| Development of novel treatment for malignant pleural mesothelioma using viral vector (Investigator-initiated clinical trial of gene therapy using AdSOCS3 for malignant pleural mesothelioma) | Institute for Biomedical Sciences, Division of Drug Discovery and Medical Device Development, Iwate Medical University | Tetsuji NAKA | |
| Development of a novel treatment for pediatric craniofacial deformity using human reconstructed elastic cartilage | Division of Regenerative Medicine, Institute of Medical Science, University of Tokyo | Hideki TANIGUCHI | |
Diagnostics
| Seeds Title | Affiliation | Name | |
|---|---|---|---|
| Prognosis biomarkers that can discriminate early-stage pancreatic cancer patients with worse prognosis prior to surgery | Department of Gastroenterology and Hepatology, Kochi Medical School, Kochi University | Keisuke TANIUCHI | |